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Learn more about evidence synthesis methods

Do you want to learn more about systematic reviews or other types of evidence synthesis methods? Check out our detailed guide on this topic, which provides a deeper overview, and reviews the various steps involved in these methods. This guide will also review UCI Libraries' Evidence Synthesis Service, and let you know how our librarians can help. The information below is a quick overview of the methodology.

What are evidence syntheses?

According to the Royal Society, 'evidence synthesis' refers to the process of bringing together information from a range of sources and disciplines to inform debates and decisions on specific issues. They generally include a methodical and comprehensive literature synthesis focused on a well-formulated research question. Their aim is to identify and synthesize all of the scholarly research on a particular topic, including both published and unpublished studies. Evidence syntheses are conducted in an unbiased, reproducible way to provide evidence for practice and policy-making, as well as to identify gaps in the research. Evidence syntheses may also include a meta-analysis, a more quantitative process of synthesizing and visualizing data retrieved from various studies.

Evidence syntheses are much more time-intensive than traditional literature reviews and require a multi-person research team. See this PredicTER tool to get a sense of a systematic review timeline (one type of evidence synthesis). Before embarking on an evidence synthesis, it's important to clearly identify your reasons for conducting one. For a list of types of evidence synthesis projects, see the Types of Evidence Synthesis tab.

How does a traditional literature review differ from evidence synthesis?

One commonly used form of evidence synthesis is a systematic review. This table compares a traditional literature review with a systematic review.

 

Traditional Literature Review

Systematic Review

Review Question/Topic

Topics may be broad in scope; the goal of the review may be to place one's own research within the existing body of knowledge, or to gather information that supports a particular viewpoint.

Starts with a well-defined research question to be answered by the review. Reviews are conducted with the aim of finding all existing evidence in an unbiased, transparent, and reproducible way.

Searching for Studies

Searches may be ad hoc and based on what the author is already familiar with. Searches are not exhaustive or fully comprehensive.

Attempts are made to find all existing published and unpublished literature on the research question. The process is well-documented and reported.

Study Selection

Often lack clear reasons for why studies were included or excluded from the review.

Reasons for including or excluding studies are explicit and informed by the research question.

Assessing the Quality of Included Studies

Often do not consider study quality or potential biases in study design.

Systematically assesses risk of bias of individual studies and overall quality of the evidence, including sources of heterogeneity between study results.

Synthesis of Existing Research

Conclusions are more qualitative and may not be based on study quality.

Bases conclusion on quality of the studies and provide recommendations for practice or to address knowledge gaps.

Types of Evidence Synthesis

Evidence synthesis refers to any method of identifying, selecting, and combining results from multiple studies. For help selecting a methodology, please refer to:

 

Types of evidence synthesis include: 

​​Systematic Review

  • Systematically and transparently collect and categorize existing evidence on a broad question of scientific, policy or management importance
  • Compares, evaluates, and synthesizes evidence in a search for the effect of an intervention
  • Time-intensive and often take months to a year or more to complete
  • The most commonly referred to type of evidence synthesis. Sometimes confused as a blanket term for other types of reviews

Systematized Literature Review

  • Not a true evidence synthesis review, but employs certain elements of a systematic review
  • No specific methodology; does not require a protocol or critical appraisal of the evidence
  • Conducted by only 1 or 2 people
  • May be completed in about 2-6 months

​​Literature (Narrative) Review

  • Not a true evidence synthesis review, but a broad term referring to reviews with a wide scope and non-standardized methodology
  • Search strategies, comprehensiveness, and time range covered will vary and do not follow an established protocol

​Scoping Review or Evidence Map

  • Systematically and transparently collect and categorize existing evidence on a broad question of scientific, policy or management importance
  • Seeks to identify research gaps and opportunities for evidence synthesis rather than searching for the effect of an intervention
  • May critically evaluate existing evidence, but does not attempt to synthesize the results in the way a systematic review would.(see EE Journal and CIFOR)
  • May take longer than a systematic review
  • See Arksey and O'Malley (2005) or Peters et al (2020) for methodological guidance

​Rapid Review

  • Applies Systematic Review methodology within a time-constrained setting
  • Employs methodological "shortcuts" (limiting search terms for example) at the risk of introducing bias
  • Useful for addressing issues needing quick decisions, such as developing policy recommendations
  • See Evidence Summaries: The Evolution of a Rapid Review Approach

Umbrella Review

  • Reviews other systematic reviews on a topic
  • Often defines a broader question than is typical of a traditional systematic review
  • Most useful when there are competing interventions to consider

Meta-analysis

  • Statistical technique for combining the findings from disparate quantitative studies
  • Uses statistical methods to objectively evaluate, synthesize, and summarize results
  • Conducted as an additional step of a systematic review