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NIH Public Access Policy: NIHMS

Instructions and resources to help the UCI research community comply with the NIH Public Access Policy.

NIH Manuscript Submission (NIHMS) system

  • Developed by NIH,  facilitates the submission of peer-reviewed manuscripts for inclusion in PubMed Central (PMC) in support of the NIH Public Access Policy.
  • Supports the public access policies of other organizations and government agencies (see the Funders List).
  • Allows authors, principal investigators, and publishers to supply material for conversion to XML documents in a format that can be ingested by PMC
  • Provides a multi-step process when depositing a manuscript in NIHMS for inclusion in PMC. The NIHMS process requires an author to approve the deposited files and associated funding before conversion and the PMC-ready version after conversion. See the five-step process summary below: 
  1. Deposit Files: Image users-Image001.jpg
    A manuscript may be submitted by the author, the PI, the publisher, or another third party. Third-party submitters must designate an author or PI to serve as the Reviewer for an NIHMS submission. In these cases, the Reviewer will receive notification of the deposit via e-mail.
  2. Initial Approval:  Image users-Image002.jpg
    The Reviewer reviews the submission to confirm or adds associated funding. The Reviewer either rejects or approves the material for processing in NIHMS.

  3. NIHMS Conversion:  Image users-Image003.jpg 
    NIHMS staff reviews the approved files for completeness, and complete submissions are converted to archival XML. The PMC-ready documents (Web and PDF versions) are checked to ensure they accurately reflect the submitted files. An e-mail notification is sent to the Reviewer when the record is available for final review.

  4. Final Approval:  Image users-Image004.jpg
     The Reviewer reviews the PMC-ready documents (Web and PDF versions) and either requests corrections or approves them for inclusion in PMC. Final Approval is required to complete manuscript processing in NIHMS.

  5. PMCID Assigned: Image users-Image005.jpg
    A PMCID is assigned when Final Approval is complete and the manuscript is matched to a PubMed record with complete citation information. For details, see When will a PMCID be assigned to my manuscript? in the NIHMS FAQ.

Image users-Image006.jpg

Manuscript is made available in PMC following the publisher-required embargo period (if applicable).

Coming Soon: A New NIH Manuscript Submission (NIHMS) System!

Coming Soon: A New NIH Manuscript Submission (NIHMS) System!
NLM Tech Bull. 2019 Nov-Dec;(431):b10.

2019 December 06 [posted]

Reflecting the National Library of Medicine's (NLM) ongoing commitment to public access support at the National Institutes of Health (NIH) and beyond, we are pleased to announce that a new NIHMS system will be released in early 2020. This new system aims to streamline the submission process, ensure the continued quality of manuscripts made publicly accessible, and give authors and investigators more transparent options for avoiding processing delays.

Those familiar with the current NIHMS system will find the basic steps of submitting, reviewing, and approving manuscripts for inclusion in PMC unchanged in the new system. They will see an updated user interface that simplifies the login process for returning users; provides contextual help throughout; and offers user-friendly options for importing article metadata, requesting corrections, and taking over the Reviewer role for stalled submissions. A video with details of these updates and more is available at:

By investing in NIHMS, our goal is to continue to ensure the public has access to publicly and privately funded research results. Please contact the NIHMS help desk if you have any questions. We’ll continue to provide updates as an official release date becomes available.

The NIH developed the NIHMS system to facilitate the submission of peer-reviewed manuscripts for inclusion in PubMed Central (PMC) in support of the NIH Public Access Policy. NIHMS has been operated by the NLM since its inception in 2005 and has processed over 725,000 submissions in that time. In the ensuing years, it has expanded to support the public access policies of numerous other funding organizations and government agencies.


Last updated: 06 December 2019

Navigating the NIH Manuscript Submission Process

The NIHMS system supports manuscript depositing into PubMed Central (PMC) as required by the public access policies of NIH and other participating funding agencies. The two parts 9.5-minute video provides detailed help with submitting, reviewing and approving your manuscript in the NIH Manuscript Submission (NIHMS) system. (Part 1: Submission and Initial Approval. Part 2: Review and Final Approval (begin at 6 min 40 sec).


A New NIH Manuscript Submission (NIHMS) System

Presented September 11, 2019. Interested in learning about genes and sequences but don't know how to begin? This webinar, intended for people with limited experience working with sequence information, will provide you with basic knowledge on how to find and compare nucleotide and protein sequences. You will learn about the kinds of data available for genes and sequences, how to select the most informative records, and how to find related genes and sequences using pre-computed information and the BLAST sequence search service.

How to Get Help@UCI

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